Dr. Charalambous serves as the Director of the TB Sequel Project at The Aurum Institute in South Africa, sharing overall responsibility for the project’s deliverables with Andrea Rachow, ensuring their direction and oversight, as well as supporting the implementation across all project areas.
Holding a medical degree from Wits University and a PhD in Epidemiology from the London School of Hygiene and Tropical Medicine, Dr. Charalambous is also the Group Chief Scientific Officer at the Aurum Institute. Her involvement in HIV programme implementation dates back to 1998, before the introduction of antiretroviral therapy, playing a pivotal role in the first large-scale antiretroviral project within Anglo American companies from 2003 to 2007.
As the main recipient of a significant PEPFAR grant, her work extended to HIV programme implementation across private practices, public hospitals, and correctional services from 2008 to 2012. Dr. Charalambous has contributed to both operational and clinical research, including Phase III trials for TB treatment and microbicides, as well as programmatic cluster randomized trials.
Presently, she is the Principal Investigator for numerous research studies and clinical trials focusing on TB and HIV, with specific interest in Post-TB lung disease, TB case finding, addressing TB in special populations, and the integration of TB and HIV care.